User contributions for Kristina
Jump to navigation
Jump to search
23 May 2012
- 12:5612:56, 23 May 2012 diff hist +11,804 N CYP1A2 Regioselectivity Created page with "==Overview== <br /> The information about possible metabolites of a drug candidate is desirable in the earliest stages of drug development, but the experimental testing of bi..."
- 12:3812:38, 23 May 2012 diff hist −2 CYP3A4 Regioselectivity No edit summary
- 12:3712:37, 23 May 2012 diff hist −4 HLM Regioselectivity No edit summary
- 12:3612:36, 23 May 2012 diff hist −10 P450 Substrates No edit summary
- 12:3612:36, 23 May 2012 diff hist −4 P450 Inhibitors →Technical information
- 12:3212:32, 23 May 2012 diff hist −1,931 CYP3A4 Regioselectivity →Interface
- 12:3212:32, 23 May 2012 diff hist 0 N File:Cyp3a4 regioselectivity.png No edit summary
- 12:3112:31, 23 May 2012 diff hist +13,737 N CYP3A4 Regioselectivity Created page with "==Overview== <br /> The information about possible metabolites of a drug candidate is desirable in the earliest stages of drug development, but the experimental testing of bi..."
- 10:5610:56, 23 May 2012 diff hist 0 N File:Hlm regioselectivity.png No edit summary
- 10:5510:55, 23 May 2012 diff hist −75 HLM Regioselectivity No edit summary
- 10:4010:40, 23 May 2012 diff hist +11,388 N HLM Regioselectivity Created page with "==Overview== <br /> The information about possible metabolites of a drug candidate is desirable in the earliest stages of drug development, but the experimental testing of bi..."
- 10:3210:32, 23 May 2012 diff hist 0 N File:P450 Substrates.png No edit summary
- 10:3110:31, 23 May 2012 diff hist +11,041 N P450 Substrates Created page with "==Overview== <br /> Biotransformations of the molecule affect clearance rate of the drug, duration of the therapeutic effect, and formation of toxic metabolites that can have..."
- 10:2810:28, 23 May 2012 diff hist −2 P450 Inhibitors →Overview
- 10:2710:27, 23 May 2012 diff hist 0 N File:P450 Inhibitors.png No edit summary
- 10:2610:26, 23 May 2012 diff hist +11,461 N P450 Inhibitors Created page with "==Overview== <br /> Cytochrome P450 is the main enzyme family responsible for xenobiotic metabolism in human organism. Inhibition of these enzymes is among the main causes of..."
22 May 2012
- 13:3913:39, 22 May 2012 diff hist +35 MRDD →Interface
- 13:3613:36, 22 May 2012 diff hist 0 N File:MRDD Cautions.png No edit summary
- 13:3613:36, 22 May 2012 diff hist 0 N File:MRDD results.png No edit summary
- 13:3513:35, 22 May 2012 diff hist +6,613 N MRDD Created page with "==Overview== <br /> This module estimates maximum recommended daily dose (MRDD) that can be used for humans in clinical trials. Description and data compilation of MRDD value..."
- 13:0413:04, 22 May 2012 diff hist 0 N File:HERG PubChem.gif No edit summary current
- 13:0413:04, 22 May 2012 diff hist 0 HERG Inhibition →Interface
- 13:0313:03, 22 May 2012 diff hist 0 N File:Herg inhibition.png No edit summary
- 13:0013:00, 22 May 2012 diff hist −88 HERG Inhibition →Overview
- 12:5612:56, 22 May 2012 diff hist +12,232 N HERG Inhibition Created page with "==Overview== <br /> Studies of hERG potassium ion channel inhibition constitute an emerging field in pharmacological safety research. Interactions of drugs hERG channel may l..."
- 11:5611:56, 22 May 2012 diff hist −96 Solubility in DMSO →Interface
- 11:5511:55, 22 May 2012 diff hist 0 N File:DMSO validation.gif No edit summary current
- 11:5411:54, 22 May 2012 diff hist 0 N File:Dmso solubility.png No edit summary
- 11:5411:54, 22 May 2012 diff hist +7,531 N Solubility in DMSO Created page with "==Overview== <br /> DMSO (dimethylsulfoxide) is recognized as the most powerful of any readily available organic solvent. It dissolves the great variety of organic substances..."
- 08:3608:36, 22 May 2012 diff hist −96 P-gp Substrates →Interface
- 08:3208:32, 22 May 2012 diff hist 0 N File:Pgp Substrate Probability.png No edit summary
- 08:3208:32, 22 May 2012 diff hist 0 N File:Pgp Substrate Classification.png No edit summary
- 08:3108:31, 22 May 2012 diff hist +8,287 N P-gp Substrates Created page with "==Overview== <br /> P-glycoprotein (P-gp) is a clinically relevant efflux transporter that extrudes compounds from a large variety of cells. Its function has been associated ..."
- 08:1908:19, 22 May 2012 diff hist −1,149 P-gp Inhibitors No edit summary
21 May 2012
- 13:4213:42, 21 May 2012 diff hist 0 N File:Pgp Inhibitor Probability.png No edit summary
- 13:4213:42, 21 May 2012 diff hist 0 N File:Pgp Inhibitor Classification.png No edit summary
- 13:2313:23, 21 May 2012 diff hist +9,436 N P-gp Inhibitors Created page with "==Overview== <br /> P-glycoprotein (P-gp) is a clinically relevant efflux transporter that extrudes compounds from a large variety of cells. Its function has been associated ..."
- 10:5910:59, 21 May 2012 diff hist 0 N File:Active transport.png No edit summary
- 10:5910:59, 21 May 2012 diff hist −39 Active Transport →Interface
- 10:5810:58, 21 May 2012 diff hist +8,959 N Active Transport Created page with "==Overview== <br /> Active transport module offers classification methods for the prediction of the compound transport across intestinal membrane by oligopeptide transporter ..."
- 10:5110:51, 21 May 2012 diff hist +3 Oral Bioavailability →Traffic-lights system explanation
- 09:1109:11, 21 May 2012 diff hist −1 Oral Bioavailability →Interface
- 09:1109:11, 21 May 2012 diff hist +9 Oral Bioavailability →Interface
- 07:5707:57, 21 May 2012 diff hist −1,345 Oral Bioavailability No edit summary
- 07:5107:51, 21 May 2012 diff hist 0 N File:Oral bioavailability simulation.png No edit summary current
- 07:5007:50, 21 May 2012 diff hist 0 N File:Oral bioavailability.png No edit summary
- 07:5007:50, 21 May 2012 diff hist +12,137 N Oral Bioavailability Created page with "==Overview== <br /> This module predicts human oral bioavailability for new compounds using a combination of two methods - probabilistic and "mechanistic". First, the "mechan..."
18 May 2012
- 13:4313:43, 18 May 2012 diff hist −3,562 LogP No edit summary
- 13:3413:34, 18 May 2012 diff hist 0 N File:Logp consensus.png No edit summary
- 13:3313:33, 18 May 2012 diff hist 0 N File:Acdlogp galas.png No edit summary